At Witherbloom, the College of Essence Studies, mages draw power from the opposing forces of life and death. These mages brew their spells from natural components and the essence of living creatures, using that power to heal or harm the living or to raise or entreat the dead. They can cause entire forests to blossom out of nowhere or call down old curses that scourge flesh from bone. Some Witherbloom mages defend ecosystems from pollution, while others revel in the power of corruption. They're at home riding zombie crocodiles down a languid river, picking herbs for a potion to treat a disease, brooding over a chorus of swamp frogs, or summoning fearsome avatars of nature. Witherbloom Campus is tucked away in a wide bayou to the southeast of the Academy's central campus.

The College of Obscure and Shadowy Talents conducts many of its classes here, as does the College of Warfare, Combat, and Academia.

Sedgemoor, the bayou area that encompasses the Witherbloom campus, is known for a range of swamp creatures: bats, crocodilian monsters, zombified animals, lumbering beasts called brackish trudges, and canine creatures called groffs. Sedgemoor is an excellent place to find pest mascots, herbs, spider silk, fungi, and other ingredients for potions and spells.

The center of the Witherbloom campus is Widdershins Hall, a bog mansion that looks like it grew out of Sedgemoor itself. Widdershins is a network of interconnected wooden pods, with planked walkways leading out of it like tendrils. The hall has a cozy inner chamber where students gather for classwork.

A stinking, thoroughly unpleasant marshland lies adjacent to Sedgemoor: the Detention Bog. Witherbloom faculty members send misbehaving students to this bog as punishment, but it's also an excellent place to gather herbs for certain cures and curses.